Spermatogonium-Derived Complete Hydatidiform Mole

نویسندگان

چکیده

A complete hydatidiform mole (CHM) is a conceptus with only sperm-derived chromosomes. Here, we report on CHM genomic DNA identical to that of the paternal somatic cells. The developed in woman who had undergone intrauterine implantation blastocyst obtained through vitro injection presumed round spermatid into one her oocytes. was genetically peripheral white cells husband and contained no maternally derived nuclear DNA. We hypothesize spermatogonium, rather than spermatid, inadvertently selected for procedure. gestational trophoblastic neoplasia, which resolved after chemotherapy. (Funded by Japan Society Promotion Science.).

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Trend of complete hydatidiform mole.

INTRODUCTION Complete Hydatidiform mole is one of the most frequent abnormal pregnancies. This review studies the trend of complete mole in Paropakar Maternity and Women's hospital and clinical ability to detect it. METHODS This is a retrospective study of 504 cases of complete hydatidiform mole recorded at Paropakar maternity and women's hospital, Kathmandu, during 2058-2065 B.S. Medical rec...

متن کامل

Ruptured Complete Hydatidiform Mole in the Fallopian Tube

Tubal pregnancies are common but presence of hydatidiform mole in tube is a rare entity. A woman of 53years presented with acute abdomen, preoperative pregnancy test was positive and ultrasonography suspected the case as hydatidiform mole in right tube. The patient was treated with total abdominal hysterectomy with bilateral salpingo-oophorectomy as her family was completed. Subsequent histopat...

متن کامل

Prophylactic Chemotherapy In High Risk Complete Hydatidiform Mole

The study was done with the aim to find out the effect of prophylactic chemotherapy on regression pattern of serum β-HCG and on the incidence of persistent trophoblastic disease in patients with high risk complete hydatidiform mole. Methods Out of 43 patients of complete hydatidiform mole diagnosed over a period of 1 year, 24 were categorised as high risk on the basis of Curry criteria. After s...

متن کامل

Establishment and characterization of cell lines derived from complete hydatidiform mole

Gestational trophoblastic diseases (GTDs) are a group of diseases characterized by abnormal cellular proliferation of atypical trophoblasts. A hydatidiform mole is an abnormal pregnancy caused by genetic fertilization disorders, and it can be classified as a complete hydatidiform mole (CHM) or a partial hydatidiform mole. The aim of this study was to establish cell lines from CHMs and to charac...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: The New England Journal of Medicine

سال: 2021

ISSN: ['0028-4793', '1533-4406']

DOI: https://doi.org/10.1056/nejmoa2005756